Journal of Innovative Optical Health Sciences, Vol. 6, Issue 2, 1350010 (2013)
OPTICAL COHERENCE TOMOGRAPHY OF ADIPOSE TISSUE AT PHOTODYNAMIC/ PHOTOTHERMAL TREATMENT IN VITRO
IRINA YU. YANINA1,*, NATALIA A. TRUNINA1, and VALERY V. TUCHIN1,2,3
- 1Physics Department, Saratov State University, Saratov, 83 Astrakhanskay str., Russian Federation, Russia 410012
- 2Laboratory of Laser Diagnostics of Technical and Living Systems of Precise Mechanics and Control Institute of the Russian Academy of Sciences, 24 Rabochaya Str., Saratov, Russian Federation, Russia 410028
- 3Optoelectronics and Measurement Techniques Laboratory, University of Oulu, P. O. Box 4500, FIN-90014 Oulu, Finland
Temporal changes in structure and refractive-index distribution of adipose tissue at photodynamic/ photothermal treatment were studied with OCT in vitro. Ethanol-water solutions of indocyanine green (ICG) and brilliant green (BG) were used for fat tissue staining. CW laser diode (808 nm) and LED light source (442 and 597 nm) were used for irradiation of stained tissue slices. The data received supporting the hypothesis that photodynamic/photothermal treatment, induces fat cell lipolysis during a certain period of time after light exposure.
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