Main > Chinese Optics Letters >  Volume 6 >  Issue 5 >  Page 323 > Article
  • Abstract
  • Abstract
  • References (15)
  • Cited By (4)
  • Get PDF
  • Paper Information
  • Received: Nov. 23, 2007

    Accepted: --

    Posted: May. 20, 2008

    Published Online: May. 20, 2008

    The Author Email: Bin Wu (


  • Get Citation
  • Copy Citation Text

    Bin Wu, Qingkang Wang. Design optimization of highly sensitive LSPR enhanced surface plasmon resonance biosensors with nanoholes[J]. Chinese Optics Letters, 2008, 6(5): 323

    Download Citation

  • !Citations Alert
  • Share
Chinese Optics Letters, Vol. 6, Issue 5, 323 (2008)

Design optimization of highly sensitive LSPR enhanced surface plasmon resonance biosensors with nanoholes

Bin Wu* and Qingkang Wang

Author Affiliations

  • National Key Laboratory of Micro/Nano Fabrication Technology, Key Laboratory for Thin Film and Microfabrication Technology of Ministry of Education, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200030


For breaking through the sensitivity limitation of conventional surface plasmon resonance (SPR) biosensors, novel highly sensitive SPR biosensors with Au nanoparticles and nanogratings enhancement have been proposed recently. But in practice, these structures have obvious disadvantages. In this study, a nanohole based sensitivity enhancement SPR biosensor is proposed and the influence of different structural parameters on the performance is investigated by using rigorous coupled wave analysis (RCWA). Electromagnetic field distributions around the nanohole are also given out to directly explain the performance difference for various structural parameters. The results indicate that significant sensitivity increase is associated with localized surface plasmons (LSPs) excitation mediated by nanoholes. Except to outcome the weakness of other LSP based biosensors, larger resonance angle shift, reflectance amplitude, and sharper SPR curves’ width are obtained simultaneously under optimized structural parameters.


Please Enter Your Email: