Main > Chinese Optics Letters >  Volume 2 >  Issue 8 >  Page 477 > Article
  • Abstract
  • Abstract
  • References (8)
  • Suppl. Mat.
  • Cited By (0/0)
  • Get PDF
  • Paper Information
  • Received: Jan. 16, 2004

    Accepted: --

    Posted: Jun. 6, 2006

    Published Online: Jun. 6, 2006

    The Author Email: Hua Mo (mohuawuli@vip.sina.com)

    DOI:

  • Get Citation
  • Copy Citation Text

    Hua Mo, Ping He, Ning Mo. Effect of helium-neon laser on fast excitatory postsynaptic potential of neurons in the isolated rat superior cervical ganglia[J]. Chinese Optics Letters, 2004, 2(8): 477

    Download Citation

  • Category
  • Medical Optics and Biotechnology
  • Share
Chinese Optics Letters, Vol. 2, Issue 8, 477 (2004)

Effect of helium-neon laser on fast excitatory postsynaptic potential of neurons in the isolated rat superior cervical ganglia

Hua Mo1,*, Ping He2, and Ning Mo2

Author Affiliations

  • 1Department of Physics, Guangxi Medical University
  • 2Department of Pharmacology, Guangxi Medical University, Nanning 530021

Abstract

The aim of this study is to further measure the effect of 632.8-nm helium-neon laser on fast excitatory postsynaptic potential (f-EPSP) of postganglionic neurons in isolated rat superior cervical ganglia by means of intracellular recording techniques. The neurons with f-EPSP were irradiated by different power densities (1-5 mW/cm2) laser. Irradiated by the 2-mW/cm2 laser, the amplitude of the f-EPSP could augment (P<0.05, paired t test) and even cause action potential at the end of the first 1-2 minutes, the f-EPSP could descend and last for 3-8 minutes. But the amplitude of the f-EPSP of neurons irradiated by the 5-mW/cm2 laser could depress for the irradiating periods. The results show that: 1) the variation of the amplitude of f-EPSP caused by laser is power density-dependent and time-dependent; 2) there exist the second-order phases in the interaction of the helium-neon laser with neurons. These findings may provide certain evidence in explanation of the mechanisms of clinical helium-neon laser therapy.

keywords